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Emulsifiers

A Common Food Additive May Be Messing With Your Brain

Psychology Today reported:

If you want to invent a new food additive, the U.S. Food and Drug Administration (FDA) requires a safety study before approval. These studies must show that the additive is healthy for humans — but it doesn’t test the effects on gut microbes. That’s a major oversight because we now know that gut microbes are enormously important for our health.

A recent study by Lee-Yan Sheen and colleagues from the National Taiwan University, found that many emulsifiers, especially synthetic ones, cause changes to the gut microbiome. Emulsifiers are additives that help oil and water mix, and they create a smooth mouthfeel that manufacturers prize. They are found in a surprisingly large number of processed foods, including peanut butter, bread, sausage, and ice-cream.

The researchers found that emulsifiers helped bacteria to invade the mucus layer lining the gut. Mucus is the first line of defense we have against pathogens, so this is concerning. With the mucus compromised, microbes and their toxins find it easier to pass through the gut lining and enter the bloodstream. The researchers found evidence of systemic inflammation as a result and an uptick in metabolic disorders including increased blood sugar levels and insulin resistance.

Some studies suggest that emulsifiers can have negative effects on gut health, including: 
  • Altering gut microbiota: Emulsifiers can alter the composition and activity of gut microbiota. For example, a 2021 study found that the synthetic emulsifiers carboxymethylcellulose and polysorbate 80 can have a lasting negative impact on gut microbiota. 
  • Causing inflammation: Emulsifiers can cause inflammation in the gut. For example, emulsifiers can increase the permeability of the gut barrier, which can lead to inflammation. 
  • Worsening inflammatory bowel disease (IBD): Emulsifiers can worsen IBD. 
  • Promoting metabolic syndrome: Emulsifiers can promote metabolic syndrome, a complex condition that includes obesity, insulin resistance, hypertension, and hyperlipidemia. 
  • Increasing the risk of colorectal cancer: A 2021 study found that dietary emulsifiers may be a new risk factor for colorectal cancer. 
  • Worsening food allergies: Emulsifiers can worsen food allergies. 
Emulsifiers are used in many foods, including:
  • Low-fat Greek yogurts
  • Trail mix bars
  • Oat milk
  • Pastries and cakes
  • Breads
  • Meat products 
The original food safety assessments for emulsifiers were done before much was known about the gut microbiome.

Tartrazine

Yellow 5, also known as tartrazine or FD&C yellow #5, is a synthetic yellow food dye suspected of being linked to health problems ranging from allergies to hyperactivity in kids to cancer. It is one of several azo food dyes made from petroleum products and among several dyes and food additives studied for potential health impacts. Video | More info

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